In September of 2006, 17 girls based on Concordia College's campus came together to initiate the first meeting to establish Theta Zeta Upsilon. The group was founded on Christian values.
 
On December 7, 2006 Concordia's Student Government Association (SGA) approved the sorority.
 
Theta Zeta Upsilon's first official event, Darkside of θZ(Y), took place on March 14, 2007.
 
Other dates include:
 
February 10, 2007, when 13 founding sisters crossed over.
 
November 10, 2007, when the 8 sisters of the Beta class crossed over.

November 6, 2008, when the 9 sisters of Gamma class crossed over.
 
November 21, 2009, when the 7 sisters of Delta class crossed over.